Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

Jorge Pincay ’20 Phosphoglycerate mutase 1 (PGAM1) is a gene known to promote rapid tumor growth and invasiveness in several cancers, including non-small cell lung cancer (NSCLC). PGAM1 encodes for an enzyme that catalyzes the conversion of 3-phosphoglycerate to 2-phosphoglycerate in the glycolytic pathway,  a compound that coordinates anabolic biosynthesis. In many forms of cancer, including NSCLC, urothelial bladder cancer, and hepatocellular carcinoma, upregulation of … Continue reading Potential for Enhanced Cancer Therapy by Allosteric Inhibition of Phosphoglycerate Mutase

Enhanced mRNA Gene Therapy for Critical Limb Ischemia

Jorge Pincay ‘20 Critical limb ischemia (CLI) is a cardiovascular condition characterized by severely narrowed arteries resulting from the buildup of plaque. This narrowing of the arteries  significantly reduces blood flow to the hands, feet, and legs and may lead to amputation of the affected limbs. Most patients suffering from CLI need to undergo some form of a revascularization procedure in order to combat this … Continue reading Enhanced mRNA Gene Therapy for Critical Limb Ischemia

Lasers, micro-needling, and platelet-rich plasma

By Ellie Teng ‘21 Advances in skin treatments have expanded to laser therapy, micro needling, and platelet rich plasma to restore and reverse the effects of aging and scarring or pigmentation. Restoring tone and reversing the effects of environmental and genetic aging through non surgical modalities have attracted a great deal of attention for their reduced downtime, risk of complication, and sufficient treatment outcomes. The … Continue reading Lasers, micro-needling, and platelet-rich plasma

Figure 1. A general counseling setting.

The Setbacks of Evidence Based Counseling

By: Ramanjot Singh ’19 In the recent years, there has been a strong wave of focus on evidence-based psychology. The push is towards achieving an evidence-based assessment for psychological conditions. More specifically, being able to have a physical test that will determine if you have a certain ailment or not. Counseling psychologist, Dr. Angie Cucchi, hypothesized that the evidence-based treatment would not be sufficient to … Continue reading The Setbacks of Evidence Based Counseling

Positive Psychology Interventions May Enhance Happiness

by Amanda Ng (’18) In an effort to help those dealing with depression and enhance general happiness, recent psychological treatments have focused on advancing a field called “positive psychology”. “Positive psychology” focuses on strategies and intentional activities to enhance a person’s well-being by inducing positive emotions and behaviors. In this study, led by Dr. Sara Wellenzohn of the University of Zurich, Switzerland, a positive psychology … Continue reading Positive Psychology Interventions May Enhance Happiness