Author: Young Investigators Review

The Young Investigators Review is Stony Brook University's undergraduate-oriented, all-inclusive science journal. Founded in 2008, our mission is to provide the student community with a way to learn more about the research currently being done on-campus by their faculty and fellow peers. We feature articles that span all fields, from Physics to Neuroscience, as well as original student research reports straight from the campus laboratories. Our journal offers aspiring talented future researchers and physicians a way to hone their science writing skills and spread word of their experiences to inspire incoming students to think about devoting their futures to the various fields of science.
Health, Neurology, Neuroscience, Psychology

Where Do We Feel Love?

Julia Chivu ‘ 23 Figure 1  A person looking off to the side while clutching a neon red heart in a dimly lit environment.  Love has compelled psychologists, philosophers, neuroscientists, and other scholars to try and understand its complexities and implications. Researchers from Aalto University sought to understand how 27 different types of love, including parental, romantic, sexual, and religious love, are perceived and experienced … Continue reading Where Do We Feel Love?

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Brain, General Neuroscience, Neurology, Neuroscience

PD-Modeling Midbrain Dopamine Loss Diminishes Thalamocortical Signaling

Vignesh Subramanian ’24 Figure 1: The substantia nigra (SN) nucleus in the midbrain. Parkinson’s disease (PD) is an age-related, neurodegenerative movement disorder that causes a progressive loss of motor control. The disease is characterized by a loss of dopaminergic (DA) neurons in the substantia nigra (SN), a midbrain nucleus that modulates movement and reward functions. The SN is one of five subcortical nuclei that make … Continue reading PD-Modeling Midbrain Dopamine Loss Diminishes Thalamocortical Signaling

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Neurology, Psychology

Maternal Empathetic Cortical Responses Synchronize with Neonatal Pain Perception

Vignesh Subramanian ‘ 24 Figure 1: The heel prick of an infant’s foot, which often induces momentary pain for the infant. The early psychophysical development of newborns relies heavily on having strong emotional bonds with caregivers. Compared to other animals, human infants are born highly dependent on their parents, undergoing a prolonged period of extensive neural organization and brain development that requires greater parental sensitivity … Continue reading Maternal Empathetic Cortical Responses Synchronize with Neonatal Pain Perception

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Biology, Ecology

Positive effects of Saccharina latissima kelp on coastal ocean acidification and growth of bivalves. 

Maria Sazonova ’26  Figure 1: Saccharina Latissima kelp underwater Coastal zones are focal points of ocean acidification due to the influx of atmospheric CO2 which has severe negative effects on the growth and survival of calcifying bivalves. Kelp species provide numerous ecosystem services such as carbon and nitrogen sequestration and the creation of a safe habitat for aquatic creatures. Saccharina latissima (sugar kelp) specifically can … Continue reading Positive effects of Saccharina latissima kelp on coastal ocean acidification and growth of bivalves. 

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Neuroscience

Prairie Vole Monogamy: key in understanding neural underpinnings of love

Jessica George ’24 Figure 1 Prairie voles are small rodents known for their unusual monogamous behavior Love and attachment hold a very important place in human lives but the neuroscience behind them is poorly understood. Recent groundbreaking research involving prairie voles helped to unravel the biological mechanisms behind love and bonding. Prairie voles are small rodents known for their unusual monogamous behavior, forming long-term pair … Continue reading Prairie Vole Monogamy: key in understanding neural underpinnings of love

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Health and Medicine, Neuroscience

Nicotine exposure discovered to block aromatase activity in healthy women

Jessica George ’24 Figure 1 Nicotine use disorder has a profound impact on hormones, yet sex differences are poorly understood. Maintaining a harmonious sex-hormone balance is essential for the optimal functioning of the body, as it regulates a wide range of physiological processes. Aromatase serves as the critical enzyme responsible for the conversion of androgens into estrogens, a process fundamental to functions associated with emotional … Continue reading Nicotine exposure discovered to block aromatase activity in healthy women

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Cellular and Molecular Science

Enhancing Cell Production Using Low Intensity Vibration (LIV)

Julia Chivu ’23 Figure 1   Scientist with blue gloves adding hot pink cell growth medium using a transfer pipette into a six-well plate, with culture flask and centrifuge tube also filled with hot pink cell growth medium in the background. Biomanufacturing is a field of study which produces various biotechnology-based products including vaccines, biofuels, and genetically modified crops by using living organisms and cells. The cells … Continue reading Enhancing Cell Production Using Low Intensity Vibration (LIV)

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Brain, Neurology

Understanding the Neurobiology of Love and Deception

Julia Chivu ’23 Figure 1  Couple holding hands walking towards a multi-colored sunset Recent scientific research has been increasingly focused on better understanding the complex relationship between deception and love. The study of deception within relationships and across genders is essential for interpreting the correlation between human behavior, neural mechanisms, and trust. A research team from Zhejiang Normal University investigated the neurological mechanisms of deception … Continue reading Understanding the Neurobiology of Love and Deception

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Neuroscience

Radiation-Induced Cognitive Decline Impairs Hippocampal Neurogenesis

Vignesh Subramanian ’24 Figure 1: A radiograph captured by X-ray, which produces ionizing radiation, a form of radiation that poses risks of damage to internal tissue. Ionizing radiation is any radiation traveling in the form of electromagnetic waves or particles with enough energy to knock electrons out of the orbit of atoms. While therapies such as radiotherapy for cancer are intended to emit ionizing radiation … Continue reading Radiation-Induced Cognitive Decline Impairs Hippocampal Neurogenesis

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Drug Discovery, Pharmacology, Psychology

Microglial Depletion Promotes Maternal Behavior in Nulliparous Rats

Vignesh Subramanian ’24 The period during and immediately following childbirth, known as the peripartum period, is marked by major changes in the mother’s hormone levels, immune function, and neurological activity. These changes include structural brain alterations with a significant impact on postpartum behaviors, such as maternal-infant bonding, that are essential for the well-being of the offspring. Many neuroimmune alterations emerging in late pregnancy remain unclear … Continue reading Microglial Depletion Promotes Maternal Behavior in Nulliparous Rats

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Announcements, YIWC

2023 YIWC is ongoing!

For the fourth year in a row, the Young Investigators Writing Competition is open for applications!As always, the winner of each category will have their piece published in our Young Investigators Review Fall Journal. Our Fall 2022 and Spring 2023 journals can be read here (the entries of the winners of YIWC 2022 start on page 34 of the Fall 2022 edition).The deadline has been … Continue reading 2023 YIWC is ongoing!

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YIWC, YIWC 2022

Xenotransplantation: The Future of Medicine

Jessica Penna, 11th Grade Solid organ transplantation, the only remedy to end-stage organ failure, is a relied upon practice for thousands of patients every year. Whether it be for kidneys, lungs, livers, or hearts, a patient can only get new organs through donation from a healthy patient or, from the most frequent source, a brain dead (BD) patient (1)(2). However, reliance on BD patients for … Continue reading Xenotransplantation: The Future of Medicine

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