Tag: aging

2024-25, Cognition, Degenerative Disease, Disease, General Neuroscience, Health, Health and Medicine

Green Tea: Fighting Dementia One Cup at a Time

Sean Krivitsky, Class of 2026 Dementia is a progressive neurological disease most prevalent in older adults that is associated with aging and significant declines in cognitive function and memory. It has been strongly correlated with general brain atrophy, including of the hippocampus, and the increased presence of lesions (areas of damage within brain tissue) in cerebral white matter. This corresponds to the symptoms observed in … Continue reading Green Tea: Fighting Dementia One Cup at a Time

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2024-25, Biology, Genetics, Health

Unraveling Chronological Age: Epigenetic Modifications as Indicators of Cognitive Decline

Author: Tiffany Ang, Class of 2025 Figure 1: A visualization of epigenetic modifications that shape gene expression without changing the genetic code. DNA methylation-derived epigenetic clocks are powerful tools for assessing biological aging and age acceleration–the difference between biological and chronological age. Unlike chronological age, which fails to capture the impact of biological and environmental influences, age acceleration explains individual differences in cognitive functions such … Continue reading Unraveling Chronological Age: Epigenetic Modifications as Indicators of Cognitive Decline

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2023-24, Cognition, Neuroscience

Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

Author: Vignesh Subramanian, Class of 2024 Figure 1: Increasing evidence suggests biological aging, measured by examining the extent of methylation of cells’ DNA, is a stronger predictor of diminishing cognitive abilities than chronological age.  Title: Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age Age acceleration is the term used to describe the difference between an individual’s chronological age, the length of time … Continue reading Epigenetic Age Acceleration More Accurately Predicts Memory Decline Than Chronological Age

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2022-23, Biology, Health and Medicine, Neuroscience

Type 2 Diabetes Accelerates Brain Aging-Related Neurocognitive Decline

Vignesh Subramanian ’24 Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease characterized by dysfunctions relating to hyperglycemia, the state of high glucose levels in the bloodstream. Such excessive blood sugar is typically the combinatory result of inadequate secretion of insulin (a hormone that directs cells and the liver to take up glucose for energy and long-term storage, respectively), uncontrolled secretion of glucagon (an … Continue reading Type 2 Diabetes Accelerates Brain Aging-Related Neurocognitive Decline

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2021-22, discovery

Reprogramming Cells May Reverse the Aging Process

Sooraj Shah ’24 Aging is a natural process by which cells are progressively unable to divide as efficiently as before, causing cell death and lysis as the functions of the cell slowly begin to decline. The main contributor to this are the telomeres at the end of our chromosomes. Telomeres get shorter as cells divide because replication cannot copy the “lagging end” of the chromosome. … Continue reading Reprogramming Cells May Reverse the Aging Process

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Uncategorized

Muscle Preservation and Metabolism-Associated Genes Show Activity During Diapause

Joyce Chen ’23 As time progresses, all living organisms will age, decay, and perish. However, there are certain animal species that can halt their biological clocks and no longer develop. This state is known as diapause. The African Killifish are known organisms that can undergo diapause in order to survive unfavorable conditions, such as dry periods in the environment. Many of these fish remain in … Continue reading Muscle Preservation and Metabolism-Associated Genes Show Activity During Diapause

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Cognition

Green Tea Could Help Reduce Signs of Aging and Improve Cognitive Functions

Thumyat Noe ’23 Green tea is one of the most consumed beverages in the world. Consumption of green tea is associated with health benefits such as improved mental health, better global cognition memory, and reduced risk of neurocognitive disorders. Researchers have attributed beneficial effects of drinking green tea to catechins which are flavonoids with antioxidant properties. During the manufacturing and brewing processes, green tea catechins … Continue reading Green Tea Could Help Reduce Signs of Aging and Improve Cognitive Functions

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Sociology

Ageing: The Role of Ageism

Thumyat Noe ’23 Although the global average life expectancy has increased, there is little evidence to support that quality of life for older people has improved. Older adults are believed to be experiencing better health worldwide due to improvements in medical, psychological, and social resources, but the role of ageism in determining healthy aging is often disregarded. Ageism is a form of prejudice in which … Continue reading Ageing: The Role of Ageism

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Disease

Higher Education Correlates to Later Onset of Alzheimer’s

Priyanshi Patel ‘22 Professors including Sean Clauston, Dylan Smith, and many others of the Public Health and Department of Family, Population, and Preventative program at Stony Brook University wanted to examine the association between education and the incidence of accelerated cognitive decline. Alzheimer’s disease and related dementias (ADRD) affect 5.4 million people in the United States and are the cause of the fifth most common … Continue reading Higher Education Correlates to Later Onset of Alzheimer’s

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Biology, Evolution, Health, Health and Medicine

21st Century Mind: The Effects of Blue-Light on the Brain, Retinas, and Rate of Aging

Mariam Malik ‘22 Blue light from electronic devices, such as smartphones and laptops, is of shorter wavelength on the light spectrum, thereby giving off higher amounts of energy. The harmful effects of absorbing too many light rays, such as UV and micro, have been researched and known. However, a recent study at Oregon State University on Drosophila melanogaster, the common fruit fly, shows the damaging … Continue reading 21st Century Mind: The Effects of Blue-Light on the Brain, Retinas, and Rate of Aging

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Drug Discovery, Evolution, Health and Medicine, Natural World

Is Eternal Life Actually Possible? New Drug Formula May Reverse Biological Age

Joyce Chen ’23 Biological age is the measurement of the true ages of humans through the chemical changes in their DNA. Previous research and hypotheses inferred that reversing this can allow humans to acquire better immune systems and healthier bodies in general. To test if biological age reversal is actually possible, determined scientists from Intervene Immune and the University of California, Los Angeles, completed a … Continue reading Is Eternal Life Actually Possible? New Drug Formula May Reverse Biological Age

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2017-18

Lymphatic Vessels Can Improve Cognition Relative to Age

Caleb Sooknanan ‘20 Aging is often associated with increased neurological problems among humans, and more research is needed to understand how lymphatic vessels connecting the brain and the immune system affect conditions such as Alzheimer’s disease. Doctor Jonathan Kipnis and researchers from the University of Virginia enhanced the lymphatic vessels of aging mice and significantly improved their abilities to learn and retain memory. The researchers … Continue reading Lymphatic Vessels Can Improve Cognition Relative to Age

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