Is Eternal Life Actually Possible? New Drug Formula May Reverse Biological Age

Joyce Chen ’23 Biological age is the measurement of the true ages of humans through the chemical changes in their DNA. Previous research and hypotheses inferred that reversing this can allow humans to acquire better immune systems and healthier bodies in general. To test if biological age reversal is actually possible, determined scientists from Intervene Immune and the University of California, Los Angeles, completed a … Continue reading Is Eternal Life Actually Possible? New Drug Formula May Reverse Biological Age

Lymphatic Vessels Can Improve Cognition Relative to Age

Caleb Sooknanan ‘20 Aging is often associated with increased neurological problems among humans, and more research is needed to understand how lymphatic vessels connecting the brain and the immune system affect conditions such as Alzheimer’s disease. Doctor Jonathan Kipnis and researchers from the University of Virginia enhanced the lymphatic vessels of aging mice and significantly improved their abilities to learn and retain memory. The researchers … Continue reading Lymphatic Vessels Can Improve Cognition Relative to Age

Can Common Signs of Aging be Reversed?

Samara Khan ‘19 The process of human aging is generally considered to be inevitable. As we become older, the collagen and elastin in our skin breaks down, causing fine lines and wrinkles to form. Our bodies stop producing melanin, and our hair turns gray and eventually falls out. While there are many cosmetic products that can improve the appearance of sagging skin and thinning hair, … Continue reading Can Common Signs of Aging be Reversed?

The Effects of the Gut on Fruit Flies’ Lifespans

By Caleb Sooknanan ‘20 Aging and chronic diseases are often associated with effects such as metabolic and oxidative stresses, inflammation, and mitochondrial deficiencies. Scientists have suggested that changes in organisms’ gut microbiota relate to specific gut phenotypes, while probiotics can be ingested to regulate chronic disease progression in conjunction with microbiota changes. However, more research is needed to understand how gut microbiota could be attributed … Continue reading The Effects of the Gut on Fruit Flies’ Lifespans

Visualizing the Impacts of Age and Disease on the Brain

By Fatin Chowdhury ‘19 Alzheimer’s disease (AD), a common neurodegenerative disorder, has previously been found to increase atrophy rate of the hippocampus, an area of the brain associated with learning and memory. In relation to this issue, Dr. Daniel H. Adler and researchers from the University of Pennsylvania recently examined specific structural details of the human hippocampus as relevant to advanced age and AD. Thirty-one … Continue reading Visualizing the Impacts of Age and Disease on the Brain

Figure 1. Reduced insulin signaling maintains “youthful” response in aging flies and can potentially prevent age-related neuronal decline.

Reduced Insulin Levels Can Prolong Neuron Longevity

By Maryna Mullerman ’20 Reduced insulin-like signaling (IIS) can lead to diabetes and damage of neuronal function in metabolism. However, chronically lowered insulin/insulin-like growth factor (IGF) may improve neurodegenerative disease defects. Hrvoje Augustin and researchers at University College London analyzed the escape response mechanism of the fly Drosophila melanogaster and the effects of genetically weakened insulin signaling on this model. This was done to explore … Continue reading Reduced Insulin Levels Can Prolong Neuron Longevity