Author: Young Investigators Review

The Young Investigators Review is Stony Brook University's undergraduate-oriented, all-inclusive science journal. Founded in 2008, our mission is to provide the student community with a way to learn more about the research currently being done on-campus by their faculty and fellow peers. We feature articles that span all fields, from Physics to Neuroscience, as well as original student research reports straight from the campus laboratories. Our journal offers aspiring talented future researchers and physicians a way to hone their science writing skills and spread word of their experiences to inspire incoming students to think about devoting their futures to the various fields of science.
Cancer, Health, Health and Medicine

Application of Trispecific Antibodies to Anticancer Immunotherapy

Ashley Goland ’23 Immunotherapy is a form of cancer treatment that utilizes the body’s own immune system to destroy cancerous tumors and has shown promise in past animal and clinical human trials. For all of its dazzling successes to date, however, immunotherapy is not completely effective for treating the full range of cancer types and patients— yet. Scientists working in Sanofi Research and Development believe … Continue reading Application of Trispecific Antibodies to Anticancer Immunotherapy

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Astronomy, Ecology, Environment, Evolution, Natural World

Implications of Solar Geoengineering

Ashley Goland ’23 Solar geoengineering is a technology that aims to reflect incoming sunlight away from the Earth to reduce the rise of global temperatures, and one proposed approach is to send aerosols into the atmosphere. Although this method may seem like a quick, relatively cheap way to delay further climate change, the effects it could have upon marine and terrestrial organisms are not yet … Continue reading Implications of Solar Geoengineering

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Brain, General Neuroscience

Breeding can Change Dogs’ Brains

Ayesha Azeem ‘23 For centuries, humans have been breeding domestic dogs with the intention of producing specific skill sets needed to improve humans’ lives. For example, purpose-bred dogs can be used for hunting or as service dogs that guide people with disabilities. Dog breeding has been highly controversial lately, since dogs are now seen more as companions rather than workers. In a new study conducted … Continue reading Breeding can Change Dogs’ Brains

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Disease, General Psychology, Health, Health and Medicine

Comfort Eating and Cortisol Reactivity

Ayesha Azeem ‘23 “Comfort-eating,” or increased food intake, is one of the most common responses to stressful situations. Cortisol is the body’s main stress hormone that regulates metabolism and the immune response to stressful situations. Cortisol reactivity under stress can predict stress-related eating behavior and how it affects the body mass index (BMI). Based on one’s cortisol reactivity to a stressor, a person may be … Continue reading Comfort Eating and Cortisol Reactivity

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Disease, Health, Health and Medicine

Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

Simran Kaur ‘20 Acute respiratory distress syndrome (ARDS) is characterized by the build-up of fluid in the alveoli of the lungs, the main sites of gaseous exchange, causing a lack of oxygen in the body. ARDS is caused by sudden trauma to the lungs, and there currently is no pharmacological treatment for the condition. Researchers in the study sought to determine the efficacy of dexamethasone, … Continue reading Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

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Cancer, Cellular and Molecular Science, Health and Medicine, Medicine and Physiology

Different Types of Anesthesia can Impact Breast Cancer Metastasis.

Priyanshi Patel ‘22 Metastasis refers to the surgical removal of solid tumors and metastasis is the main cause of cancer death. Previously, not much was known about the role anesthetics play in cancer metastasis. Complete surgical removal of solid tumors offers the possibility of a cure and is the basic treatment provided. Despite surgery, recurrent metastasis in vital organs does reoccur and is a major … Continue reading Different Types of Anesthesia can Impact Breast Cancer Metastasis.

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Environment, Natural World

Countdown to 2050 to Save the Amazon.

Priyanshi Patel ‘22 The number of fires in the Amazon last year had renewed public concern for the future of the region’s forest biome. The concerns date back to the early 1970s when Brazil made the Transamazon Highway, after which the rate of deforestation increased. One of the principal questions Amazon scientists are asking is, how much deforestation and global climate change can the Amazon’s … Continue reading Countdown to 2050 to Save the Amazon.

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General Psychology, Genetics, Natural World, Psychology

Examining the Benefits of Unique Coloration for Male Trinidad Guppies

Fatin Chowdhury ’20 The predisposition of organisms in seeking certain phenotypic traits in mates is an oft-observed aspect of the natural world, with sexual selection being a well-studied phenomenon. However, unique coloration specifically often seems to be more linked to lessened survivability (due to an inability to camouflage in environments), or phenomena such as aposematism, where unique colors serve as a warning for predators. In … Continue reading Examining the Benefits of Unique Coloration for Male Trinidad Guppies

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Chemistry, Environment, Natural World

Herbaceous Layer Dynamics in Central Appalachian Hardwood Forests

Fatin Chowdhury ’20 Forests are stratified in sections such as the herbaceous layer, which includes tracheophytes (plants with vasculature) over 1 meter in height and can be extremely ecologically significant. Potential factors influencing forest dynamics in this context include top layer (overstory) characteristics and soil quality. A researcher at the University of West Florida, Frank S. Gilliam, recently conducted work at the Fernow Experimental Forest … Continue reading Herbaceous Layer Dynamics in Central Appalachian Hardwood Forests

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Biology, Psychology, Sociology

How Do We Recognize Dog Emotions?

Ayesha Azeem ‘23 We humans are very complex creatures. When we spend a lot of time in close association with a species, we tend to treat them as if they are humans as well, and we can decipher their emotions clearly. With the expression of emotions, we can communicate our motivations, responses and needs to others. Recognizing animals’ emotions can be beneficial, as it may … Continue reading How Do We Recognize Dog Emotions?

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Brain, Cellular and Molecular Science, General Neuroscience, Sociology

Genetics and the Brain

Ayesha Azeem ‘23 Our society currently witnesses an underrepresentation of females in most ‘heavy’ science and mathematics fields, including technology and engineering. Though some may argue that the unfair proportions are due to biological differences, little evidence supports this claim. Scientists study biological differences in the brain, and the brains of males and females are more similar than not. Though behavioral studies often find no … Continue reading Genetics and the Brain

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Biology, General Psychology, Health and Medicine, Sociology

How Relaxing Music Affects Sleep

Ayesha Azeem ‘23 Sleep is vital for maintaining physical and mental health and general well-being. However, our society often witnesses sleep disturbances, especially as we get older and in those who suffer from psychological disorders. However, many people, especially the elderly or those suffering from psychological disorders, experience sleep disturbances. Though some may use sleep-inducing medication, this may not be as effective as toleration can … Continue reading How Relaxing Music Affects Sleep

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