Richard Zaher, Grade 10 With the coming of the new millennium, the world has experienced the implementation of the use of technology to an extent that is extremely unprecedented. From inventions that seem so sophisticated like the James Webb Hubble Telescope in 2022, or something so valuable yet so ordinary in today’s world like the iPhone, technology has truly revolutionized how we live our lives … Continue reading Do We Drive Forward?
By: Kimberly Johnston, Class of 2026 Figure 1: A marine turtle Adult female marine turtles alternate between foraging and nesting phases, with periods of migration in between. Monitoring programs typically obtain data for only part of the nesting season due to a lack of financial support, remote beaches, or a large number of beaches to monitor. To accurately assess population trends, a model must be … Continue reading Modeling Marine Turtle Nesting Behavior
By: Kimberly Johnston, Class of 2026 Figure 1: Gentoo penguin with chicks at Port Lockroy, Antarctica. Antarctic tourism has raised concerns about the effects of human disturbance on gentoo penguins during their breeding season, which coincides with peak tourist activity. For example, the movement of zodiacs used to transport tourists ashore can disrupt the penguins’ normal routes and foraging areas. However, quantifying the effects of … Continue reading Penguin Nesting Behavior: Effects of Tourism at Port Lockroy
By Vignesh Subramanian, Class of 2024 Figure 1: A myelinating oligodendrocyte in a murine brain. Oligodendrocytes are specialized glial cells in the central nervous system primarily responsible for myelination, the process of ensheathing the axons of neurons in a lipid-rich membrane known as myelin, which insulates the nerve fibers and speeds up the transmission of the action potentials they conduct. Oligodendrocytes are the products of … Continue reading Mature Oligodendrocytes Demonstrate Delayed Cell Death by Alternate Mechanism
Marie Collison, Class of ‘25 Individuals who have experienced childhood maltreatment (CM) in their past have a greater risk of exhibiting behaviors of maltreatment towards their own children. As such, it is important to understand how mothers may respond to their infant cues in context with their past experiences, especially during the often tumultuous postpartum (after-birth) period. Prior research has established that brain responses in … Continue reading Childhood Maltreatment as a Predictor of Neural Activity During Postpartum
By: Marie Collison, Class of ‘25 Depression is a very common and impairing condition, often resulting in costly care. Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed as a part of treatment; however, 30–50% of individuals who are prescribed antidepressants do not take them long-term. There are many reasons why a patient may decide to stop taking their medication, such as experiencing negative side effects … Continue reading Understanding SSRI Withdrawal: Insights Into the Complex Journey
Marie Collison, Class of ‘25 Image 1 Gentoo penguins in Antarctica Marine pollution is a prominent problem in environmental policy and study. Reports of pollution in organisms in the Antarctic are becoming increasingly common, likely due to increasing human activity, growing tourism, and an expanding krill fishing industry. However, the sources of these pollutants along the West Antarctic Peninsula are still poorly understood. There are … Continue reading Modeling Debris Patterns in the Antarctic to Protect Biodiversity
Author: Sean Krivitsky, Class of 2026 Parkinson’s disease is a severe neurodegenerative disorder most commonly occurring in late adulthood. It is primarily characterized by motor dysfunctions such as uncontrollable tremors and stiffness. Since there is no conclusive test for diagnosis of the disorder, neurologists rely on a comprehensive evaluation system, combining symptoms and physical assessments to gauge the likelihood that an individual has Parkinson’s. A … Continue reading Uncovering a Novel Biomarker For The Identification of Parkinson’s-Related Diseases
Author: Sean Krivitsky, Class of 2026 To the astonishment of many, nearly 99% of the human genome consists of non-coding regions that are not transcribed into mRNAs for protein synthesis. However, some of those non-coding regions of DNA can be transcribed into various types of non-coding (nc) RNAs, including long ncRNAs. Until recently, the scientific community believed these ncRNA products to be functionally irrelevant, playing … Continue reading Mysterious Long Non-Coding RNAs Revealed as Playing a Role in Gastric Cancer
Author: Vignesh Subramanian, Class of 2024 Figure 1: Barnes maze tests were performed to assess the spatial reference memory of the knock-in AD mouse models. Alzheimer’s disease (AD) is a progressive, neurodegenerative disease characterized by significant memory loss and cognitive decline that worsen with age. While the disease’s long-established hallmarks include the aggregation of two misfolded proteins known as beta-amyloid and phosphorylated tau, recent research … Continue reading Inhibition of Hydrolytic Enzyme May Protect Against Manifestation of AD-Linked Phenotypes
Vignesh Subramanian, Class of 2024 Figure 1: A thrombectomy is a surgical procedure aimed at removing blood clots lodged in an artery of the brain. A stroke is a medical emergency in which blood flow to the brain is disrupted. Strokes may be ischemic (lacking blood supply to brain tissue due to a blocked artery) or hemorrhagic (involving bleeding into the brain tissue due to … Continue reading Neuroprotective Therapies Capable of Ameliorating Ischemic Injury in Post-Thrombectomy Care
Author: Sean Krivitsky, Class of 2026 Rett syndrome (RTT) is a severe neurological disorder found primarily in females that causes impairment in essential functions including breathing, eating, and walking abilities. The disorder is characterized by slowed brain growth, which can lead to various mental and physical disabilities. Key markers and causes of RTT are mutations on a gene called MECP2. MECP2 is an X-linked gene … Continue reading Uncovering a Key Mechanism of Rett Syndrome Pathology
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