Fall 2020 SBYIR Journal Theme: Sensory Science

“Sensory Science” Sensory perception is an integral part of everyday life and its applications are cross-disciplinary. Sensory science is a broad scientific theme that involves not only the perception, measurement and analysis of the five basic senses (sight, smell, touch, taste, and hearing), but also includes the perception of other senses (such as pain), the technological applications and development of sensors, and the ecological study … Continue reading Fall 2020 SBYIR Journal Theme: Sensory Science

Announcing the Young Investigators Writing Competition

Calling all Long Island 9th-11th grade students! The Stony Brook Young Investigators Review is excited to launch our very first scientific writing competition! If you would like an outlet to engage your interests in science and writing from home, this is an opportunity for you! To enter, you will compose a 750-1000 word article that analyzes a controversy in one of the following categories: biology, … Continue reading Announcing the Young Investigators Writing Competition

Application of Trispecific Antibodies to Anticancer Immunotherapy

Ashley Goland ’23 Immunotherapy is a form of cancer treatment that utilizes the body’s own immune system to destroy cancerous tumors and has shown promise in past animal and clinical human trials. For all of its dazzling successes to date, however, immunotherapy is not completely effective for treating the full range of cancer types and patients— yet. Scientists working in Sanofi Research and Development believe … Continue reading Application of Trispecific Antibodies to Anticancer Immunotherapy

Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

Simran Kaur ‘20 Acute respiratory distress syndrome (ARDS) is characterized by the build-up of fluid in the alveoli of the lungs, the main sites of gaseous exchange, causing a lack of oxygen in the body. ARDS is caused by sudden trauma to the lungs, and there currently is no pharmacological treatment for the condition. Researchers in the study sought to determine the efficacy of dexamethasone, … Continue reading Dexamethasone as a Possible Treatment for Patients Diagnosed with Acute Respiratory Distress Syndrome

Countdown to 2050 to Save the Amazon.

Priyanshi Patel ‘22 The number of fires in the Amazon last year had renewed public concern for the future of the region’s forest biome. The concerns date back to the early 1970s when Brazil made the Transamazon Highway, after which the rate of deforestation increased. One of the principal questions Amazon scientists are asking is, how much deforestation and global climate change can the Amazon’s … Continue reading Countdown to 2050 to Save the Amazon.

Cardiovascular Health Benefits to Dog Ownership

Aditi Kaveti ‘23 Loneliness and depression — in addition to a lack of physical activity — can increase the risks associated with health complications and premature death. Previous studies have demonstrated the links dog ownership has with increased physical activity, reduced social isolation, and lower blood pressure. A new study conducted by Professor Tove Fall at Uppsala University in Sweden suggested that dog ownership could … Continue reading Cardiovascular Health Benefits to Dog Ownership

Short-term relationships with violent men make women more prone to gender violence

Joyce Chen ‘23 Violence against women is a common occurence worldwide. In many countries, women are sexually abused or suffer from human trafficking. However, more research is needed to uncover the underlying factors that predispose women to such violence. Researchers under Lídia Puigvert utilized the ‘Free Teen Desire’ experimental project to study the link between females’ attractions to males and future gender violence as a … Continue reading Short-term relationships with violent men make women more prone to gender violence

All Eyes and Ears: How Visual Deprivation Enhances Auditory Learning in Adult Mice

Mariam Malik ‘22 Past research and work has proven the interconnectedness of all senses and their corresponding cortices in the brain. For example, it has been scientifically proven that those lacking in one sense possess advanced abilities in others. Cross-modal learning, or the manipulation of one sense to cause alterations in another, is a key feature of further research. Researchers at the University of Maryland … Continue reading All Eyes and Ears: How Visual Deprivation Enhances Auditory Learning in Adult Mice

Study Reveals Ability of Human Cartilage to Regenerate

Mariam Malik ‘22 Cartilage is malleable soft tissue meant to prevent excess friction from joints rubbing against one another. Located in numerous parts of the body, such as the larynx, respiratory tract, and the septum, human cartilage is the most malleable and widespread at birth, eventually being replaced by bone. For a long time, scientists believed that cartilage in joints could not be regrown; however, … Continue reading Study Reveals Ability of Human Cartilage to Regenerate

Biodiversity Offers Insight into the Ecosystem of Liver Cancer

Priyanshi Patel ’22 Liver cancer is the second most lethal malignancy in the world and includes mainly hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). HCC is the most common type of primary liver cancer and often occurs in people with chronic liver diseases. iCCA is also a cancer that develops within the bile duct, whereas HCC occurs among alcoholics or those with fat accumulation in … Continue reading Biodiversity Offers Insight into the Ecosystem of Liver Cancer

Essential Role of the MEKK3-ERK5 Module in Endothelial Cell Death

Jorge Pincay ’20 Atherosclerosis is a chronic inflammatory disease characterized by the build-up of plaque in artery walls, which can lead to coronary artery disease, heart failure, and stroke. Since atherosclerosis results from endothelial cell injury and death, researchers are making greater efforts to acquire a better understanding of the cellular mechanisms that may lead to these unfavorable changes in endothelial cells. In particular, the … Continue reading Essential Role of the MEKK3-ERK5 Module in Endothelial Cell Death

Can a Reduction in Carbohydrate Consumption Produce Adverse Effects?

Jorge Pincay ’20 Low carbohydrate  diets (LCD) have been adopted by many patients as a means of battling diseases such as cancer, diabetes, obesity, and many other metabolic disorders. This type of diet is even widely used by the general population for maintaining and/or losing weight. However, not many studies  have investigated the adverse health effects that may result from a sudden halt in carbohydrates … Continue reading Can a Reduction in Carbohydrate Consumption Produce Adverse Effects?