An Enzyme-Activating Protein may be a Switch for Invasive Cancer

Zhifei Zeng ’23 Many breast cancer (BC) patients suffer from complications of metastatic disease. In order to form metastasis, cancer cells must switch from a proliferative to an invasive state and overcome several physical barriers to reach another site. Interestingly, increased invasiveness of the tumor is accompanied by a decrease in its cell proliferation capacity. For breast cancer, some proteins may help this proliferative-to-invasive switch … Continue reading An Enzyme-Activating Protein may be a Switch for Invasive Cancer

Making Magic in Medical Settings: How Magic May Improve the Patient-Student Connection

Thumyat Noe ’23 Many medical students often find themselves feeling emotionally detached from the illness experiences of patients. To combat this sentiment, medical education curricula recommend that students gain clinical immersion experience early to enhance students’ awareness of the patient experience. Past clinical findings suggest that performing magic acts as part of clinical immersion experience can further improve relations between medical staff and child patients. … Continue reading Making Magic in Medical Settings: How Magic May Improve the Patient-Student Connection

Investigating Interleukin-17 Activity: One Step Closer to Treating Crohn’s Disease?

Sooraj Shah ’24 About 3 million Americans have been diagnosed with Crohn’s disease, a type of inflammatory bowel disease (IBD), with foreboding statistics indicating a rise in the disease’s prevalence. Crohn’s disease debilitates a patient through inflammation of the digestive tract, leading to severe pain and cramping in the abdominal area. The inflammation associated with the IBD is a response to invading pathogens by a … Continue reading Investigating Interleukin-17 Activity: One Step Closer to Treating Crohn’s Disease?

The Role of OCD in Oral Health of Affected Individuals

Thumyat Noe ’23 Obsessive-compulsive disorder (OCD) is a mental health disorder characterized by disturbing thoughts and repetitive behaviors. Presentations of OCD include excessive cleaning and extreme fixation with symmetry or order. Psychiatrists treat OCD through prescribing antidepressants and selective serotonin uptake inhibitors. According to previous studies, mental health disorders can reduce oral health by increasing inflammatory biomarkers. However, OCD patients exhibit unique obsessions with cleaning … Continue reading The Role of OCD in Oral Health of Affected Individuals

Discrimination During COVID-19 Exacerbates Academic Disconnect of Asian Students

Zhifei Zeng ’23 Since January 2020, the world has been suffering from a pandemic brought about by COVID-19. In addition to the direct health threat posed by the virus, a survey showed that the rate of racist and xenophobic attacks against Asians increased all over the globe, especially in the United States. In fact, the Stop AAPI Hate Reporting Center has reported 3,800 hate crimes … Continue reading Discrimination During COVID-19 Exacerbates Academic Disconnect of Asian Students

Novel Early Childhood Predictors for Eating Disorders Give Hope for Improved Treatment

Peter Gillespie ’25 Eating disorders are dangerous and severely impairing mental illnesses that have become extremely prevalent in our youth, affecting up to 13% of young women in particular. Previous studies have identified risk factors, such as sleeping habits and parental eating tendencies, but these findings are inconsistent and focus solely on adolescents, limiting their scope. Dr. Garbrielle Carlson at Stony Brook University researches risks … Continue reading Novel Early Childhood Predictors for Eating Disorders Give Hope for Improved Treatment

How the Motor Cortex Plays a Role in Parkinson’s Disease

Ayesha Azeem ’23 Parkinson’s Disease is a brain disorder that leads to shaking, stiffness, and difficulty with walking and balance. The symptoms gradually begin and get progressively worse over time. Although neuroscientists understand the role of neuron and dopamine loss in Parkison’s Disease, little is known about how dopaminergic modulation affects brain regions that are involved in the control of voluntary movement. In the primary … Continue reading How the Motor Cortex Plays a Role in Parkinson’s Disease

Improving Cognitive Functions in World Trade Center Responders

Thumyat Noe ’23 Individuals who responded to the World Trade Center attacks on September 11th, 2001 experienced a great deal of trauma and distress. Researchers from Stony Brook University who study well-being and cognitive abilities discovered that these responders are at an elevated relative risk of developing aging-related cognitive impairment. In particular, lower cognitive function is correlated with higher levels of exposure to trauma in … Continue reading Improving Cognitive Functions in World Trade Center Responders

Does Ethnicity Influence Memory Recall in Social Settings?

Daphne Siozios ’23 Collaborative learning occurs when a group of individuals works together to remember shared information and events. Not much is known about how the collaborative learning process and a social setting aids memory formation, analysis, and recollection since past research in the field has mainly focused on studying individuals in isolation. Professor Suparna Rajaram at Stony Brook University works to examine the effect … Continue reading Does Ethnicity Influence Memory Recall in Social Settings?

Optimizing Movement-Based Behavior Networks in Artificial Intelligence

Ishmam Khan ’25 Deep learning involves the use of machinery to simulate biological phenomena, especially human behavior. Researchers have developed two systems of programming that proved useful in mimicking movements: convolutional neural networks (CNNs), which are based on virtual imagery and spatial information, and recurrent neural networks (RNNs), which adapt long-short term memory (LSTM) to model long term contextual information of temporal sequences.  When used … Continue reading Optimizing Movement-Based Behavior Networks in Artificial Intelligence

Glial Cells May Shape Brain Tumor Microenvironments

Alex Moir ’23 Glial cells, located in the central nervous system (CNS), support neurons by clearing extracellular waste and mounting an immune response against potential pathogens. Glioma are tumors occurring in the CNS that originate from these glial cells. As glioma tumors progress and become more aggressive, they invade surrounding tissue and develop a hospitable tumor microenvironment (TME). Two types of resident CNS immune cells, … Continue reading Glial Cells May Shape Brain Tumor Microenvironments

Release of Biological Molecules May Promote Formation of Vasculature in a Developing Embryo

Joyce Chen ’23 When an embryo develops, its cells undergo numerous rounds of cell division and arrange into a highly organized system of tissues that collectively assemble into organs. While positioning themselves at the midline, cells known as angioblasts are responsible for the formation of blood vessels in major arteries and veins. Simultaneously, somites — structures in the developing embryo that give rise to bone, … Continue reading Release of Biological Molecules May Promote Formation of Vasculature in a Developing Embryo