Nicotine exposure discovered to block aromatase activity in healthy women
Jessica George ’24 Figure 1 Nicotine use disorder has a profound impact on hormones, yet sex differences are poorly understood. Maintaining a harmonious sex-hormone balance is essential for the optimal functioning of the body, as it regulates a wide range of physiological processes. Aromatase serves as the critical enzyme responsible for the conversion of androgens into estrogens, a process fundamental to functions associated with emotional … Continue reading Nicotine exposure discovered to block aromatase activity in healthy women
Enhancing Cell Production Using Low Intensity Vibration (LIV)
Julia Chivu ’23 Figure 1  Scientist with blue gloves adding hot pink cell growth medium using a transfer pipette into a six-well plate, with culture flask and centrifuge tube also filled with hot pink cell growth medium in the background. Biomanufacturing is a field of study which produces various biotechnology-based products including vaccines, biofuels, and genetically modified crops by using living organisms and cells. The cells … Continue reading Enhancing Cell Production Using Low Intensity Vibration (LIV)
Understanding the Neurobiology of Love and Deception
Julia Chivu ’23 Figure 1 Â Couple holding hands walking towards a multi-colored sunset Recent scientific research has been increasingly focused on better understanding the complex relationship between deception and love. The study of deception within relationships and across genders is essential for interpreting the correlation between human behavior, neural mechanisms, and trust. A research team from Zhejiang Normal University investigated the neurological mechanisms of deception … Continue reading Understanding the Neurobiology of Love and Deception
Radiation-Induced Cognitive Decline Impairs Hippocampal Neurogenesis
Vignesh Subramanian ’24 Figure 1: A radiograph captured by X-ray, which produces ionizing radiation, a form of radiation that poses risks of damage to internal tissue. Ionizing radiation is any radiation traveling in the form of electromagnetic waves or particles with enough energy to knock electrons out of the orbit of atoms. While therapies such as radiotherapy for cancer are intended to emit ionizing radiation … Continue reading Radiation-Induced Cognitive Decline Impairs Hippocampal Neurogenesis
Microglial Depletion Promotes Maternal Behavior in Nulliparous Rats
Vignesh Subramanian ’24 The period during and immediately following childbirth, known as the peripartum period, is marked by major changes in the mother’s hormone levels, immune function, and neurological activity. These changes include structural brain alterations with a significant impact on postpartum behaviors, such as maternal-infant bonding, that are essential for the well-being of the offspring. Many neuroimmune alterations emerging in late pregnancy remain unclear … Continue reading Microglial Depletion Promotes Maternal Behavior in Nulliparous Rats
2023 YIWC is ongoing!
For the fourth year in a row, the Young Investigators Writing Competition is open for applications!As always, the winner of each category will have their piece published in our Young Investigators Review Fall Journal. Our Fall 2022 and Spring 2023 journals can be read here (the entries of the winners of YIWC 2022 start on page 34 of the Fall 2022 edition).The deadline has been … Continue reading 2023 YIWC is ongoing!
Xenotransplantation: The Future of Medicine
Jessica Penna, 11th Grade Solid organ transplantation, the only remedy to end-stage organ failure, is a relied upon practice for thousands of patients every year. Whether it be for kidneys, lungs, livers, or hearts, a patient can only get new organs through donation from a healthy patient or, from the most frequent source, a brain dead (BD) patient (1)(2). However, reliance on BD patients for … Continue reading Xenotransplantation: The Future of Medicine
An Overview of AI-Created Art – Philosophical, Legal, and Ethical Implications
Matthew Vo, 12th Grade The past decade has experienced dramatic growth of interest in Artificial Intelligence (AI) programs, with particular attention focused on “creative AI”, capable of producing visual artwork, writing, or music at a level of quality rivaling that of works created by human artists and authors. However, such developments have also raised pressing legal and ethical concerns, as well as philosophical questions on … Continue reading An Overview of AI-Created Art – Philosophical, Legal, and Ethical Implications
Xenotransplantation: A Potential Solution to the Organ Shortage
Jennifer Zhong, 12th Grade In the United States, over 100,000 patients are on the national organ transplant waiting list in hopes to receive the necessary transplant to save their lives [10]. However, with the growing demand for organ transplants, only one-third of those on the waitlist will receive a transplant, and it is estimated that 40% will die before an organ donor is available [2, … Continue reading Xenotransplantation: A Potential Solution to the Organ Shortage
Space Tourism: An Out of This World Experience
Charlene Chen, 11th Grade Space tourism, though often perceived as a distant and elusive dream, has already become a reality in recent years. Starting in 2001, California businessperson Dennis Tito spent 20 million USD to board a Russian Soyuz rocket heading to the International Space Station, officially earning the title of the first “space tourist” (1). More recently in 2021, several non-astronaut civilians flew into … Continue reading Space Tourism: An Out of This World Experience
The Environmental and Economic Impacts of Biofuels
Sanjiv Singh, 11th Grade While gas prices rise to historic levels, Americans have been considering other sources of fuel such as biofuel (1). From ethanol to other forms of biofuel, the economic and environmental impacts could be enormous. As gas prices skyrocket due to many factors and one being the war between Russia and Ukraine, many citizens have been unable to gain gasoline, leaving them … Continue reading The Environmental and Economic Impacts of Biofuels
The Potential Benefits of Xenotransplantation
Vivian Chen, Grade 10 Healthy organs are vital for every human’s best quality of life. Sometimes, however, organs may become diseased or damaged. When this occurs, the victim may be in need of an organ transplant. Organ transplantation is a process in which an organ is removed from a donor and transplanted into a recipient. Although this is a valid and often successful treatment, it … Continue reading The Potential Benefits of Xenotransplantation

